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[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Wayne SJ, Rhyne RL, Garry PJ, et al
Costa-Mattioli, M
suggested that ROS production increases due to NAD + reduction during aging and promotes hypoxia-inducible factor-1 (HIF-1) accumulation, leading to metabolic reprogramming, which is a hallmark of cancer
Human studies will help to further elucidate its therapeutic potential.
