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Similarly, GRO, a SASP component induced by oncogenic RAS, encourages the senescence of normal human ovarian fibroblasts [216]

[DOI] [PubMed] [Google Scholar] 36.Kolb H., Nelson R., Fernandez E., Jones B

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Additionally, chronic alcohol intake can inhibit the Nrf2-ubiquinol cytochrome c reductase core protein 2 (UQCRC2) pathway and suppress mitophagy activity by downregulating adenosine monophosphate-activated protein kinase (AMPK) gene expression

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