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Description
Arsenic trioxide is required in the treatment of newly diagnosed acute promyelocytic leukemia
Whereas in most other organs, including brain, endothelial cells form a continuous barrier that prevents cancer cells from penetrating freely
doi: 10.1016/j.biotechadv.2021.107794 33 Chvez-CabreraC.Flores-BustamanteZ
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The stated rationale was safety: immunogenicity, manufacturing impurities, and thin human clinical data
