glutathione peroxidase helps the body convert Selenoprotein 4: From Molecular Mechanisms to Novel Therapeutic Opportunities The Role of Glutathione Peroxidase-1

specific values for half-life and tissue retention vary across the literature depending on model and route of administration

It is more stable, which extends its effective window of activity

Extensive studies have been attempted to link the GSTM1 -null genotype with disease, particularly cancer

doi: 10.1111/pce.12701

Bioorg Chem 9:253260 Akaike T, Ida T, Wei FY, Nishida M, Kumagai Y, Alam MM, Ihara H, Sawa T, Matsunaga T, Kasamatsu S, Nishimura A, Morita M, Tomizawa K, Nishimura A, Watanabe S, Inaba K, Shima H, Tanuma N, Jung M, Fujii S, Watanabe Y, Ohmuraya M, Nagy P, Feelisch M, Fukuto JM, Motohashi H (2017) Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics