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By analyzing 14 cancer subtypes in TCGA multi-omics dataset, a study revealed 40 driver genes associated with the Wnt, Notch, Hedgehog, JAK/STAT, NK-KB, and MAPK signaling pathways

Neuroprotective gene therapy for huntingtons disease, using polymer-encapsulated cells engineered to secrete human ciliary neurotrophic factor: results of a phase I study

In epithelial tissues, fisetin suppressed cytokine-driven inflammation by attenuating NF-B p65 nuclear translocation and ERK1/2 phosphorylation, as well as reducing IL-6, IL-8, TNF-, ICAM-1, and CCL5 expression [59,60]

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Swain, N., Tripathy, A., Padhan, P., Raghav, S