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The therapeutic administration of ergot alkaloids may cause sporadic cases of human ergotism [151]

This indicated that CBS silencing exerted an inhibitory effect on the xCT system, which significantly reduced intracellular cysteine and GSH levels

This effect is associated with increased fat-pad deposition and elevated serum leptin levels, suggesting a role in energy homeostasis

This phenomenon may be specifically attributed to Bacteroides fragilis enrichment, which compromises intestinal barrier integrity through mucin degradation-mediated disruption of the mucosal layer (Ji et al., 2023
