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Mass spectrometry imaging identifies palmitoylcarnitine as an immunological mediator during Salmonella Typhimurium infection

After binding with PERK, TMAO selectively activates PERK-mediated UPR, thereby promoting metabolic dysfunction ( Of note, TMAO in the pathogenesis of Alzheimers disease (AD) indicated that PERK is not the only mechanism by which TMAO induces UPR
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