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PMC 9392980

Xanthohumol prevents dextran sulfate sodium-induced colitis via inhibition of IKK/NF-B signaling in mice

A 2012 study published in Journal of Pharmacology and Experimental Therapeutics demonstrated that a seven-day dihexa dosing protocol produced cognitive improvements in rodent models that persisted for at least 30 days post-treatment, despite the compound being undetectable in plasma within 12 hours of the final dose

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