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Due to the different cellular mechanisms that characterize the different MS stages, modeling the disease as a whole is not feasible with one given model

No, a single high-quality diluent is sufficient for both

TABLE 2 Summary of morphine-, heroin-, nicotine-, and alcohol-induced neurotoxicity according to their effect on the structural integrity of the BBB and their respective molecular pathways

J.PengX.et al (2012)

The tumor is accessed through the cup forceps, incisional or excisional biopsy
