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This pathological state creates an imbalance where ROS and RNS production exceeds the neutralizing ability of intrinsic antioxidant systems, thereby establishing conditions of oxidative stress (Rahman and MacNee, 2000)

First , inactivating mutations in GATA1 cause X-linked recessive diseases
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Funding This work was supported by the Natural Science Foundation of Zhejiang Province (LQ20H040008 and LY20H040009) and by the National Key Research and Development Program of China (No

Mesalazine, an osteopontin inhibitor: the potential prophylactic and remedial roles in induced liver fibrosis in rats