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However, these results do not rule out a role for GSSG as an alternative source of oxidizing equivalents for PDI

Phase II clinical trials for inflammatory bowel disease reported no toxicity or adverse events in treated patients, though detailed safety data from these trials have not been published in peer-reviewed literature

After menopause, women tend to have lower activity of enzymes involved in glutathione production compared to before menopause

Spontaneous PSSG formation depends heavily on the local GSH:GSSG ratio
