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Studies of sex differences in MTHFR polymorphism might provide some insights for the divergent results from various studies of psychiatric disorders

Access this article Similar content being viewed by others Abbreviations AGEP: Acute generalized exanthematous pustulosis ALT: Alanine aminotransferase APCs: Antigen-presenting cells AST: Aspartate aminotransferase CBZ: Carbamazepine CCR: CC-chemokine receptor COVID-19: Coronavirus disease 2019 CTL: Cytotoxic T cells CXCR: CXC chemokine receptor DiHS: Drug-induced hypersensitivity syndrome DRESS: Drug reaction with eosinophilia and systemic symptoms EBV: Epstein-Barr virus ESR: Erythrocyte sedimentation rate FasL: Fas ligand FADD: Fas-associated death domain protein HHV: Human herpesvirus HIV: Human immunodeficiency virus HLAs: Human leukocyte antigens HMGB-1: High-migration protein-1 Ig: Immunoglobulin IL: Interleukin IVIG: Intravenous immunoglobulin J-SCAR: Japanese Research Committee on Severe Cutaneous Adverse Reaction KC: Keratinocytes MCP: Monocyte chemotactic proteins MHC: Major histocompatibility complex NF-kB: Nuclear transcription factor-kappa B NK cells: Natural killer cells NSAIDs: Non-steroidal anti-inflammatory drugs TCR: T cell receptor TEN: Toxic epidermal necrolysis Th17: T helper type 17 TNF: Tumor necrosis factor RegiSCAR: European Registry of Serious Adverse Skin Reactions SCARs: Severe cutaneous adverse drug reactions SCORTEN: Score of Toxic Epidermal Necrolysis SJS: Stevens-Johnson syndrome References International drug monitoring: the role of national centres

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Lobaplatin does not cause cross-resistance to cisplatin and has shown effectiveness in overcoming cross-resistance between cisplatin and carboplatin in certain clinical tumours