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24 However, limitations to using this agent as adjunctive therapy may include the relative difficulty of obtaining preservative-free products for epidural use and the potential of ketamine to induce emergence phenomena, nausea, and vomiting

If the patient has heart failure, the nonrenal (hepatic) clearance might be halved because of hepatic congestion and hypoxia, so the expected clearance would become 5.5 L/h

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F-actin is critical to cell structure and function, playing an important role in cell migration