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Preliminary human studies involving FOXO4-axis modulators, such as high-dose fisetin, show a reduction in the senescence-associated secretory phenotype (SASP) and enhancements in cognitive and physical measures among older adults
1 Introduction Infertility is becoming a widespread global issue, and the World Health Organization estimates that 12.617.5% of couples globally encounter fertility challenges, with male factors contributing to 3050% of cases of reduced fertility (Cox et al., 2022
10.1016/j.foodres.2023.113080
These pathways influence the activity of fusion proteins (dynamin-related protein 1) and segregation proteins (mitofusin 1/2 and optic atrophy type 1), as well as mitochondrial morphology [31]
Muscle Nerve 62 , 321326 (2020)
