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doi: 10.1038/nature13908 59 ItoY.CarssK

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Therefore, melatonin can inhibit the growth of breast cancer cells in the MCF-7 and MDA-MB-231 cell lines by inducing cell death by increasing the expression of the apoptotic markers TUNEL and Bax and the autophagy Beclin-1, LC3, and p62 [37]