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For instance, by 2024, drugs such as adalimumab (Humira, AbbVie) and infliximab (Remicade, Johnson & Johnson and Merck & Co.) remain among the top-selling biologics worldwide 6

2025 Feb 10;12(5):uhaf043
N., Aman, Z

An example of the first scenario is o -succinylbenzoate synthase, which catalyzes the dehydration of 2-hydroxy-6-succinyl-2,4-cyclohexadiene carboxylate to form o -succinylbenzoate synthase in the biosynthetic pathway for menaquinone synthesis