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Levels of methylmalonic acid (MMA) and homocysteine rise, because the body needs B12 to convert them into other compounds

Data were considered parametric if they passed (alpha = 0.05) at least one of the normality tests

When Should You Investigate for B12 Deficiency

Hence, total plasma or serum B12 concentration includes B12 (cobalamin) bound to transcobalamin (holoTC) and B12 bound to haptocorrin
