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The authors of both studies attributed the results to an improvement in the intestinal absorption of fluids and electrolytes and possibly increased skeletal muscle uptake causing greater neuromuscular performance, besides a possible gluconeogenic effect of alanine, sparing muscle glycogen, and retarding fatigue [144, 146]

doi: 10.1016/j.neuint.2025.105949 2 AyalaA.MuozM

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Another study [19] reported increased serum levels of IL-1R antibody in FM patients and hypothesized the role of IL-6 toward the hypersensitivity to pain, fatigue, and depression