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Since DSIP supports deep sleep without sedative effects, it can be used without the risk of grogginess, making it easier to wake up refreshed and ready to perform
Finley and Davis, 1999)
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This may explain why the loss of dopaminergic neurons in the SN is the main pathological feature in PD, which is significantly different from AD, in which the loss of neurons in the medial temporal lobe is dominant 25
