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Furthermore, copper can stimulate the activity of an enzyme called cystathionine beta-synthase (CBS), which converts homocysteine to cystathionine in the methionine cycle

Despite these restrictions, it is still sometimes used in animal feeds, such as pet food and fish meals, which may result in ongoing human exposure

Under physiological conditions, more than 98% of the total GSH pool exists in the reduced form, thereby shaping cellular redox potential and influencing proliferation, differentiation, and cell death 5 .Although the GSH/GSSG ratio has long been regarded as an indicator of cellular redox status, recent live-cell studies using genetically encoded redox sensors indicate that increases in GSSG are typically transient and compartmentalized rather than sustained intracellular accumulations 6,7