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These include diverse microorganisms: Bacterial sources: Pseudomonas aeruginosa, Bacillus subtilis, Burkholderia cepacia known for high thermostability and broad pH tolerance Fungal sources: Penicillium species, Aspergillus niger, Rhizopus oryzae excellent for large-scale production with high yields Yeast sources: Candida rugosa, Yarrowia lipolytica preferred for food applications due to GRAS (Generally Recognized as Safe) status 2

At 6 mg/mL, 0.6 mg equals 0.1 mL, or 10 units on a U-100 syringe

This pivotal study linked diet, the gut microbiome, and heart disease via a common metabolite

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