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One such compound is the modern antiaging ingredient, GHKCu, which exhibits multiple beneficial effects but poorly penetrates the lipophilic stratum corneum

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Itoh 2005

You may wish to discuss testing with a healthcare professional if you: Experience ongoing unexplained fatigue Follow a vegan or vegetarian diet Have a history of gastrointestinal surgery or digestive conditions Have previously been diagnosed with low B12 Have symptoms such as numbness, tingling, or cognitive changes Testing helps determine whether B12 injections are appropriate or whether another cause should be investigated

Johansson, A.G., et al