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This mechanism represents a control of the influx of fatty acyl units into mitochondria in response to the intra-mitochondrial acetyl-CoA level, in addition to the finely regulated mechanism of CPT1 by malonyl-CoA

doi: 10.1016/j.nutres.2013.10.006

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Curcumin administration has been associated with beneficial changes in gut microbiota composition, leading to improved intestinal barrier function and reduced endotoxin levels that may contribute to liver inflammation through toll-like receptor (TLR) pathways

The effects of vitamin E (200 mg) supplementation, in combination with vitamin C (300 mg), and -carotene at various concentration (16.7, 8.4, 5.6, or 0 mg/day), compared with those of vitamin E alone, were evidenced in a study conducted on 276 elderly subjects aged between 60 and 75 years