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10.1080/15569543.2020.1747495 6 AlsubaieiS

Chemotherapy also targets various mitochondrial enzymes or proteins, including mitochondrial ribosome and ribosomal proteins (MRP), DNA polymerase subunit gamma (PolG), ATP synthase, and the calcium or other ion channels as the voltage-dependent anion channel 1 (VDAC1), the mitochondrial calcium uniporter (MCU) complex, and the mitochondrial permeability transition pore complex (mPTPC) [58]

First, this was only a small patient cohort study in China and further research with broader populations is needed to validate our findings

doi: 10.1097/MCG.0000000000001236 Artin Galoosian , Mona Rezapour, Benny Liu, Taft Bhuket, Robert J Wong

L-carnitine increased hepatic expression of genes related to long-chain fatty acid transport, mitochondrial -oxidation, and antioxidant enzymes following suppression of hepatic oxidative stress markers and inflammatory cytokines in NASH, and mice treated with L-carnitine developed fewer liver tumors