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Description
Claudin-2 attenuates diseases induced by luminal insults A pair of studies of Cldn2 -transgenic and Cldn2 -knockout mice provided initial evidence that increased claudin-2 expression is beneficial in dextran sulfate sodium (DSS)-induced colitis 98,99

In some embodiments, an otic composition or formulation disclosed herein comprises less than about 50 ppm of each of C1-C4 alcohols or C1-C4 glycols

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In some embodiments, the otic composition or formulation comprises less than 5% by weight of C1-C4 alcohols or C1-C4 glycols
