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While human clinical trials have not yet been completed, the existing data provides valuable insight into how the compound works and what effects it produces

Before taking any new medication, either prescription or over-the-counter, check with your doctor or pharmacist

Under conditions of compromised mitochondrial function, the PMF falls below the threshold required for ATP synthesis and the activity of ATP synthase can actually reverse such that it hydrolyzes ATP to pump protons back into the inner membrane space

this is why elevated methylmalonic acid appears in vitamin B12 deficiency