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212 Mechanistic studies found that, like trans -diamminedichloroplatinum(II), the trans -[PtCl 2 (HN=C(OMe)Me)(NH 3 )] series formed monofunctional adducts that developed into interstrand cross-links between adjacent guanine and cytosine bases

Dimethylaminomicheliolide is a novel chemotherapeutic agent that induces apoptosis and autophagy by adjusting the ROS/MAPK signaling pathway and inhibiting the Akt/mTOR signaling pathway to treat gliomas (Wang et al., 2019)

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With the use of GTE, the serum level of TT3, TT4, FT3, FT4 increased by 16%, 23%, 28%, 22% compared to the control group

Drug Design, Development and Therapy 2016;10:192733