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"N-Acetylcysteine Prevents HIV Gp 120-Related Damage of Human Cultured Astrocytes: Correlation with Glutamine Synthase Dysfunction." BMC Neurosci 8 (2007): 106
Moreover, overexpression of genes such as glutathione reductase 1 (GSR1) and glyoxalase enzyme 1 (GLO1) has been strongly correlated with anxiety phenotypes (Hovatta et al., 2005), with GLO1 inhibitors showing potential in alleviating anxiety (Distler et al., 2012)
Most PD cases are sporadic, and it is reported that 5% to 10% of PD may be caused by a single pathogenic mutation (single gene)
When comparisons were made, all relevant treatment groups were included
It has also been proposed that the hydrophobic staple motif represents an evolutionarily conserved determinant for rapid folding of the enzyme
