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A significant proportion of the cytochrome c in the mitochondria seems to be associated with cardiolipin, involving two major mechanisms

It is the same kinds of ROS and NOS modalities that oxidize and alter the structures of lipids in cellular membranes that signal for various kinds of cell death, apoptosis, ferroptosis, pyroptosis and many other death pathways (Zheng et al., 2024)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Rodrigues E.G., Bellinger D.C., Valeri L., Hasan O.S.I., Quamruzzaman Q., Golam M., Kile M.L., Christiani D.C., Wright R.O., Mazumdar M