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To target certain brain regions for electrical stimulation and regulation during DBS, an electrode is implanted in specific brain regions and high-frequency electrical stimulation (100200 Hz) is delivered to mimic the effect of a lesion without destroying brain tissue

These impending studies should incorporate objective assessments of sleep quality, utilizing polysomnography, concurrently with measurements of gut-derived metabolites, amyloid/tau biomarkers, and cognitive trajectories over time

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Additionally, oxygen is needed for ATP production

I usually reserve them for patients who need more aggressive intervention due to high metal levels