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SOD1-mutant mice exhibited mitochondrial ultrastructural pathologies in spinal cord and skeletal muscle tissues, manifesting as reduced mitochondrial length, cristae disorganization, and increased spherical fragmented mitochondria (Mendez-Lopez et al., 2021)

10.33448/rsd-v10i2.12507 24 GomesA

[DOI] [PMC free article] [PubMed] [Google Scholar] 199.Beyene A.M., Moniruzzaman M., Karthikeyan A., Min T

427 A preliminary clinical study involving five patients with platinum-resistant high-grade epithelial ovarian cancer receiving a combination of carboplatin and Trientine indicated that Trientine can partially reverse the resistance of cancer cells to platinum therapy, warranting further evaluation in larger studies