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Thalamic neurons in the midline reuniens nucleus have strong recurrent connections with the frontal cortex and hippocampus and drive corticothalamic-hippocampal network activity (Bertram et al., 2008)

The mineral oil arm (a comparator oil in the REDUCE-IT study) showed unfavorable changes in LDL-C and C-reactive protein levels resulting in increased ASCVD risk compared to the entire cohort, suggesting that the protective effect of EPA over EPA plus DHA might have been overestimated

doi: 10.1023/A:1021922305036

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Symptoms can include difficulty breathing, hives, and swelling of the face, lips, tongue, or throat [12]