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tb within in vitro granulomas harvested at both 8 days ( Figure 3F ) and 15 days post-infection ( Figure 3G )

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IV formulations can be effective, however the costs can be significant ($900 per session), factor in 4 sessions, for temporary results that typically last 3-8 weeks

As previously mentioned, other non-hepatic viruses have been linked to the development of ALF

TGR inhibitors do not react covalently with GSH, selenocysteine, or TGR, and inhibition of TGR is reversible To evaluate stability of the TGR inhibitors in the presence of GSH and selenocysteine, compound 2 and a known covalent inhibitor of TGR, TRi-1 20,45 , were incubated with GSH or the N-Boc protected methyl ester of selenocysteine, and the reaction mixtures were analyzed by LCMS (Supplementary Figs