aspirin glutathione adduct Aspirin's target in platelets: inhibits cyclo-Oxygenase-1 SCHEME 1. Proposed mechanism of
Description
J Comp Neurol 469: 115, 2004

Aggresomes are a cytoplasmic juxtanuclear structure to which misfolded proteins are actively transported in cellular states in which the capacity of the chaperone-refolding system and of the UPS is exceeded

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It is worth noting that dysregulation of DNA methylation patterns has been linked to various brain disorders, including depression, anxiety, and cognitive decline (reviewed in: 14,15 )

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