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We focused on elucidating the interaction mechanism between host-regulated specific gut microbiota (such as Eggerthellaceae, Anaerovoracaceae, Romboutsia, Atopobiaceae, Prevotellaceae_NK3B31_group, Dorea , and Frisingicoccus ) and various metabolic pathways (including pyrimidine metabolism, arginine biosynthesis, and the mTOR signaling pathway)