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However, SASP is also essential for remodeling and promoting wound healing, which requires a strict control of the inflammatory response, thus avoiding the induction of cell aging phenotypes that contribute to the development of chronic inflammatory diseases (233)

The chronic and debilitating nature of these disorders, coupled with the current lack of reliable pharmacotherapies, strongly justifies the need for treatment alternatives

(3) Checking whether the elevation persists can help identify patients who may need further investigation

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