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Anaplerosis in HF Another factor that may influence the interpretation of glucose oxidation results is the fact that pyruvate may be channeled into anaplerotic pathways (Fig

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Recent studies suggest a bidirectional relationship between TMAO metabolism and miRNA expression, adding complexity to the mechanisms linking the microbiome to cardiovascular disease (CVD)

doi: 10.1001/jama.2019.20008

Although intervention studies have partially indicated that the long-term consumption of dietary choline sources does not cause significant changes in plasma TMAO levels and there is no correlation between diets high in choline and CVD, observational studies do not support these findings
