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Having established both the accelerator (ROS) and the brake (Nrf2), we next asked whether direct inhibition of JNK would shortcircuit the entire cascade
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As a result, glutathionylated Grx and reduced substrate protein are released
10.1054/bjoc.2001.1810 143 SedoA.VlasicovK.BartkP.VespalecR.VicarJ.SimnekV.et al (2002)
and gluconeogenesis is suppressed 38 in part due to depletion of pyruvate and lactate 39
