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Tacrolimus protects hippocampal neurons of rats with status epilepticus through suppressing oxidative stress and inhibiting mitochondrial pathway of apoptosis

Step 3: Optimization phase (weeks 3-8) Based on assessment results, establish your working protocol: Dose: Your minimum effective dose (typically 75-200mcg) Frequency: 3-5 times weekly based on tolerance observations Timing: Your optimal pre-bedtime window Track results weekly and make minor adjustments as needed

Manage Stress: Emotional and physical stress increase the production of free radicals

In this study, through comprehensive screening of FDA drug library and natural product library, we identified selenomethionine as a novel ferroptosis inhibitor