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Practical take For clinicians, this reinforces a more nuanced approach: Match the drug to the patient profile Look beyond average weight loss alone Consider tolerability, adherence, comorbidities, access, and long-term strategy The obesity pipeline is getting deeperand that is good news for patients

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In some rare cases, very high levels of B12 in the blood can be associated with minor side effects like mild acne, dizziness, or a temporary rash