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Effect of Resveratrol on Endothelial Function in Patients with CKD and Diabetes: A Randomized Controlled Trial
YY1 inactivated transcription coregulator PGC-1 to promote mitochondrial dysfunction of early diabetic nephropathy-associated tubulointerstitial fibrosis

GPX3 is abundantly expressed in the kidneys, synthesized specifically in renal tubular cells and released into circulation or bound to tubular basement membranes [16]
It also suggests that NAC may act as a double-edged sword in cancer therapyincreasing persulfide levels to enhance antioxidant defense, but potentially supporting tumor growth in certain contexts

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