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Patients were also evaluated for retinopathy, peripheral neuropathy and autonomic neuropathy using Ewing's method

Prostate cancer cells may have less vitality after therapy with etomoxir, irreversible inhibitor of CPT1A, and etomoxir treatment in mice reduced xenograft growth for a period of 21 days ( CPT1A in lung cancer Lung cancer is one of the most common malignant tumors in humans, and its incidence and mortality are increasing year by year worldwide ( CPT1A in glioblastoma multiforme (GBM) GBM is the most common and difficult central nervous system malignancies, with a 5-year survival rate of 6.8% ( CPT1A in colon cancer Colon cancer develops in adipose-rich microenvironment, and CPT1A overexpression is crucial for adipocytes to promote tumor growth in colon cancer ( CPT1A in gastric cancer Gastric cancer is a malignancy of stomach lining ( CPT1A in ovarian cancer CPT1A was found to be highly expressed in ovarian cancer, and its overexpression is linked to a poor survival in ovarian cancer patients ( CPT1A in nasopharyngeal carcinoma Nasopharyngeal carcinoma (NPC) incidence can be affected by genetic susceptibility, and environmental factors

The baseline Fitzpatrick skin type of participants in the MAD study (Part E) is summarized in eTable 2