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In mammals, the activity of CBS is increased by the binding of SAM to the Bateman module 15

Functional variability across liver cell subtypes, immune cells, and metabolic tissues could produce bidirectional or even contradictory effects in different physiological contexts

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doi: 10.1002/med.21599 135 CostaEDRezendeBACortesSFLemosVS

Curcumin Attenuates Oxidative Stress in RAW264.7 Cells by Increasing the Activity of Antioxidant Enzymes and Activating the Nrf2-Keap1 Pathway