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That may sound like a small thing, but its a big change as trial sponsors in the past havent always asked that question, said Allyanna Anglim, a Pfizer spokeswoman

Each dose was tested in triplicate

Temperature accelerates this process

2010 Apr 7;4:103

Thus the solution should preferably have a pH of about 6 to 9, preferably 6,5 to 7,5
