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However, leptin replacement does not completely prevent the neuroendocrine adaptations induced by weight loss 1, 3, 5 , indicating the existence of critical additional, but still unknown, starvation signals

Regular monitoring through blood tests can help ensure your kidney function remains healthy throughout your treatment course

doi:10.3390/cancers16244234 119

Funding This study was supported by grants from the National Key Research and Development Program of China (2022YFC2503802), the Innovative Construction Foundation of Hunan Province (grant number: 2021SK4001), the National Natural Science Foundation of Hunan province,China (2023JJ30924), the National Natural Science Foundation of Changsha city, China(kq2208385), Scientific research project of Health Commission of Hunan Province (B202303076019) Ethics declarations Ethics approval and consent to participate Ethics approval and consent to participate is not applicable in this study

[12] Song D, et al