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A recent systematic review in 2024 detected that curcumin was found to upregulate several tumor-suppressive microRNAs, including miR-497, miR-200c, miR-200b, miR-409-3p, miR-34, miR-126, miR-145, miR-206, miR-491, miR-141, miR-429, miR-101, and miR-15a

Your care team will check these during treatment, but let them know if you feel dizzy, faint, or notice a rapid heartbeat

Although these findings require clinical corroboration, they nominate TRK blockade as a strategy to disable NGF-driven stromal remodeling and dissemination in osteosarcoma irrespective of fusion status

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