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, S-methyl-3-thioacetaminophen glucuronide [S-CH3-APAP-Glu], S-methyl-3-thioacetaminophen sulphoxide glucuronide [SO-CH3-APAP-Glu], the intermediate conjugated 3-thioacetaminophen glucuronide [SH-APAP-Glu], and non-conjugated S-CH 3 -APAP, Fig

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However, its pentavalent form (As 5+ ) requires active transport, and once inside the cell, it is reduced to trivalent arsenic [71,74]

Early studies in the rat compared the decidual response of young and aged ovariectomized rats and found a diminished deciduogenic response in aged rats (Ohta, 1987)

Although the kinetic model of metabolism included in the spheroid model only covers the basic GSH to GSSG oxidation reaction presented approach and system provides an opportunity for further expansion possibly with additional GSH reaction or transfer across cells and organelles