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In the central nervous system (CNS), iron has functions such as neurotransmission, gene expression, and mitochondrial electron transport (Benarroch, 2020)

[3]Veselov, M.M., Uporov, I.V., Efremova, M.V., Le-Deygen, I.M., Prusov, A.N., Shchetinin, I.V., Savchenko, A.G., Golovin, Y.I., Kabanov A.V., and Klyachko N.L. Modulation of a-Chymotrypsin Conjugated to Magnetic Nanoparticles by the Non-Heating Low-Frequency Magnetic Field: Molecular Dynamics, Reaction Kinetics, and Spectroscopy Analysis.ACS Omega20227(24), 20644-20655. DOI: 10.1021/acsomega.2c00704

Vitamin B5 (Pantothenic Acid) Supports stress resilience and adrenal health Has been shown to help regulate cholesterol levels Helps the skin form a strong barrier and supports healthy skin cell development Possible symptoms of a deficiency include: Headaches Fatigue Vitamin B6 (Pyridoxine) Supports hormonal balance, especially in the luteal phase Plays a key role in neurotransmitter production and mood regulation Can help reduce PMS-related breakouts May reduce symptoms of seborrheic dermatitis Symptoms of a deficiency: Scaly patches Red skin and dandruff Cracks in the corners of the mouth Fatigue Biotin (B7) Supports blood glucose balance Helps with fatty acid metabolism Supports hair, skin and nail health Symptoms of a deficiency (rare) can include: Hair loss Skin issues Mood changes Fatigue Theres also a link between gut health and biotin levels

Melatonin also completely restored the tenofovir associated twofold increased protein carbonylation and nine fold increased myeloperoxidase activity that explained the melatonin's ability to attenuate the tenofovir induced oxidative stress and inflammation