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GSH is also involved as an antioxidant in the detoxification of products deriving from ROS-promoted oxidation of lipids such as malonyl dialdehyde and 4-hydroxy-2-nonenal, and probably many other products of ROS interaction with cellular components (Eaton and Bammler, 1999

307 Within the cis -[Pt(en)Cl 2 X 2 ] series where X is an anionic axial ligand, the chloride species (E p = 4 mV) is much more susceptible to reduction than the carboxylate (E p = 250350 mV) or hydroxide (E p = 664 mV) derivatives

McCarty MF, OKeefe JH, DiNicolantonio JJ

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Moreover, the buildup of metabolites, energy metabolism, and the downregulation of inflammatory factor production were enhanced (540)