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doi: 10.1016/j.copbio.2016.12.001

The epidermis primarily experiences oxidative stress and reduced production of enzymes like GLO-2 under UV exposure, leading to the accumulation of AGEs and associated skin issues such as pigmentation, dullness, and wrinkles

Nojehdehi and colleagues showed that exosomes derived from the AT-MSCs of C57BL/6 mice exerted an immunomodulatory effect when administered to STZ-induced diabetic mice in a model of the same strain [90]

The gut lining is significantly damaged

Throughout the reproductive lifespan, women typically undergo over 400 cycles of endometrial regeneration, differentiation, and shedding (Lv et al., 2018)